Fetal alchol syndrome facial
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Prenatal Alcohol Exposure Alters the Patterns of Facial Asymmetry
15 Jul Fetal alcohol syndrome (FAS) is the most clinically recognizable form of FASD and is characterized by a pattern of minor facial anomalies.
The 3 Diagnostic Facial Features of FAS (All three must be present). Examples of the full (Rank 4) FAS facial phenotype across race and age (A) Caucasian, (B).
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Description:Cause[ edit ] Fetal alcohol syndrome usually occurs when a pregnant woman has more than four standard drinks per day. On the contrary, clinical and animal studies have identified a broad spectrum of pathways through which maternal alcohol can negatively affect the outcome of a pregnancy. Clear conclusions with universal validity are difficult to draw, since different ethnic groups show considerable genetic polymorphism for the hepatic enzymes responsible for ethanol detoxification. The so-called placental barrier is no barrier with respect to ethanol. The developing fetal nervous system appears particularly sensitive to ethanol toxicity. The latter impacts negatively on proliferation, differentiation, neuronal migration, axonic outgrowth, integration and fine tuning of the synaptic network.